28^th European Nephrology Conference

Tubulointerstitial Diseases

Tubulointerstitial diseases are clinically dissimilar conditions that share comparable features of tubular and interstitial damage. In severe and sustained cases, the entire kidney may turn out to be complicated, with glomerular dysfunction and even renal failure.

Tubulointerstitial nephritis is a primary injury to renal tubules and interstititum resultant in impaired renal function. The critical form is most often due to allergic drug responses or to infections. The prolonged condition form occurs with a different array of causes, including inherited or metabolic conditions, obstructive uropathy, and chronic exposure to conservational toxins or to definite drugs and herbs. Diagnosis is recommended by history and urinalysis and often confirmed by biopsy. Treatment and prognosis vary by the etiologic and potential reversibility of the syndrome at the time of diagnosis.