Kidney - Mineral & Bone disorders

The kidneys plays a significant role in sustaining healthy bone mass and structure by balancing phosphorus and calcium levels in the blood. Healthy kidneys trigger a form of vitamin D that a person consumes in food, turning it into calcitriol, the active form of the vitamin. Calcitriol helps the kidneys uphold blood calcium levels and endorses the formation of bone.

Previously, health care providers used the word “Renal Osteodystrophy” to define mineral and hormone disturbances caused by kidney disease. These days, renal osteodystrophy only describes bone problems that result from mineral and bone disorder in CKD. Health care providers might use the phrase “chronic kidney disease mineral and bone disorder,” or CKD-MBD, to refer the condition that affects the bones, heart, and blood vessels.

Mineral and bone disorder in CKD occurs when injured kidneys and abnormal hormone levels cause calcium and phosphorus levels in a person’s blood to be out of equilibrium. Mineral and bone disorder commonly occurs in people with CKD and disturbs most people with kidney failure in receipt of dialysis.


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