Genetic Kidney Disorders

Kidneys are affecting by more than 60 genetic causes either directly or indirectly. Genetic kidney conditions range from comparatively common conditions to very rare diseases. In some are associated with mild symptoms and others can cause serious health conditions.

Genetic disorders of the kidney include cystic syndromes, metabolic syndromes and immune glomerulonephritis. Cystic diseases comprise autosomal dominant and recessive polycystic kidney disease. Neonates with enlarged, cystic kidneys should be evaluated for Polycystic Kidney Diseases.

Polycystic kidney disease is a genetic disorder that causes numerous cysts to produce in the kidneys. These tumours can obstruct with kidney function and cause kidney failure.

Some of the genetic conditions


  • Cystinosis
  • Nephronophthisis
  • Autosomal Dominant Polycystic Kidney Disease
  • Autosomal Recessive Polycystic Kidney Disease
  • Thin Basement Membrane Disease
  • Gitelman and Bartter Syndromes
  • Collagen-related kidney diseases including Alport Syndrome
  • Lowe Syndrome
  • Hereditary Interstitial Kidney Disease
  • Tuberous Sclerosis

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