28^th European Nephrology Conference July 25-26, 2024 Frankfurt, Germany

Frankfurt am Main, city, Hessen Land (state), western Germany. The city lies along the Main River about 19 miles (30 km) upstream from its confluence with the Rhine River at Mainz. Pop. (2021 est.) city, 759,224; urban agglom., 3,210,500. There is evidence of Celtic and Germanic settlements in the city dating from the 1st century BCE, as well as Roman remains from the 1st and 2nd centuries CE. The name Frankfurt (“Ford [Passage or Crossing] of the Franks”) probably arose about 500 CE, when the Franks drove the Alemanni south, but the first written mention of Franconofurt stems from Charlemagne’s personal biographer, Einhard, in the late 8th century. The Pfalz (imperial castle) served as an important royal residence of the East Frankish Carolingians from the 9th century through later medieval times. In the 12th century the Hohenstaufen dynasty erected a new castle in Frankfurt and walled the town. The Hohenstaufen ruler Frederick I (Frederick Barbarossa) was elected king there in 1152, and in 1356 the Golden Bull of Emperor Charles IV (the constitution of the Holy Roman Empire) designated Frankfurt as the permanent site for the election of the German kings. Frankfurt am Main was a free imperial city from 1372 until 1806, when Napoleon I made it the seat of government for the prince primate of the Confederation of the Rhine. In 1810 the city became the capital of the Grand Duchy of Frankfurt, created by Napoleon. From 1815, when Napoleon fell, Frankfurt was again a free city, where in 1848–49 the Frankfurt National Assembly met. From 1816 to 1866 the city was the seat of the German Bundestag (Federal Diet) and thus the capital of Germany. After the Seven Weeks’ War in 1866, Frankfurt was annexed by Prussia and thereby lost its free-city status. It was only after its integration into a united Germany that Frankfurt developed into a large industrial city.